SYNAPT - G2-Si - High Definition Mass Spectrometry by Waters Corporation. Telephone and fax From the USA or Canada, phoneHPLC, or fax. Waters designed the SYNAPT® G2-Si Mass Spectrometer to be used as a research tool to deliver authenticated, exact-mass measurement. The SYNAPT G2-Si Mass Spectrometer is not intended for use in diagnostic applications. To access the highest levels of information content from your most analytically challenging samples, or utilize analytical tools to make scientific discoveries not possible by any other means, look no further than SYNAPT® G2-S. Richmond Scientific is the leading supplier of used scientific equipment and used lab equipment in the UK. The technician provides &39;.
248) in skyline, while in MassLynx when extracted with this mass, there is. Please contact us for complete Waters refu. SYNAPT G2-Si HDMS Redefining Resolution – Resolution in 3 Dimensions. Intended use of the SYNAPT G2-S Mass Spectrometer The instrument is a hybrid quadrupole/ortho gonal acceleration, time-of-flight (oa-TOF) mass spectrometer.
Manuals and User Guides for Waters SYNAPT G2. How to shut down or vent a QTof or Synapt for a planned shutdown - WKB1047; How to start up or manual of waters synapt g2 ppt pump down a powered down mass spectrometer - WKB1049; How to set up Hyperterminal - WKB17402; How to calibrate MS over an extended high mass range using sodium iodide (NaI) or similar salts in MassLynx for SYNAPT G2 and Xevo G2 and later - WKB18128. cdf&39; file as the. Ask about refurbished and used Waters mass spectrometer installation, service contracts and leasing. This allows for highly selective and sensitive characterization of compounds in complex mixtures.
Switch the epc and aux breakers to the up position. RAW directory&39; as raw data and &39;. Intended use Waters designed the MALDI SYNAPT G2-Si system to deliver authenticated, exact-mass measurement in both MS and MS/MS mode. I am trying to analyze small molecule data collected using Waters SYNAPT G2. It has an electrospray ionization (ESI) interface, meaning that analytes need to be dissolved in mixture of aqueous/organic solution (e. 1 Preparing the MALDI SYNAPT G2 HDMS System for Operation This chapter provides an overview of the system.
It describes how to install the MALDI source, set up sample plates, and set up the camera for operation. Mass resolution 50,000 at 1000 manual of waters synapt g2 ppt m/z; 35,000 at 3500 m/z; Mass accuracy < 1ppm. We have been trading for over 20 years and supply used laboratory equipment and scientific instrumentation to manufacturing facilities, research labs, contract labs as well as to many researchers, clinicians and innovators in businesses, schools and university settings. However, the chromatograms shown by Skyline look quite different from the ones by MassLynx. SYNAPT provides the most complete characterization of complex mixtures and molecules with unique levels of MS performance, industry leading in. Page 20: Waters Synapt G2 Ms ® The ACQUITY UPLC SYNAPT G2 MS UPLC /MS/MS system includes an ACQUITY UPLC system and the Waters SYNAPT G2 MS fitted with the LockSpray ESI/APCI/ESCi source.
For other locations worldwide, phone and fax numbers appear in the Waters Web site. 50% methanol/50% water or 30% acetonitrile/70% water). The Waters Synapt G2 UPLC/QTOF-MS combines ultra performance liquid chromatography with accurate mass MS, MS/MS and MS(e) with the ability to perform simultaneous ion mobility separation.
Download Waters SYNAPT G2 Operator&39;s, Overview And Maintenance Manual. IET refurbishes and certifies used Waters mass spec systems to meet manufacturer&39;s specifications complete with qualification scans. Laboratory Equipment Waters 2410 Service Manual 56 manual of waters synapt g2 ppt pages. Waters Xevo G2-XS QTof Pdf User Manuals.
We’ve combined QuanTof™ — breakthrough quantitative Tof technology — and enhanced High Definition MS™ technologies to provide you with intuitive operation, application flexibility and a. Why we need such feedback is that we are currently considering to buy a QTOF system and we will place a tender open competition to provide the best system from Waters, Agilent, Bruker, SciEX, and Leco. Refurbished Waters Synapt G2 complete with HDMS ion mobility, ETD, ESI source, pumps and Masslynx 4.
Features Quantitative quadrupole time-of-flight mass spectrometer (QuanTofTM) High resolution exact MS/MS Travelling wave ion mobility separation (TriwaveTM cell, incl. The MALDI SYNAPT G2-Si is for research use only and is not for use in diagnostic. See the instrument’s online Help for details on the system’s operation. The data types of Bruker LC-QTOF and FT-ICR, and Waters LC-Xevo QTOF and Synapt G2 were mostly centroid: you have to select ‘centroid’ as data type in the MS-DIAL program.
Wait another minute. TRAP T-Wave, IMS T-Wave, TRANSFER T-Wave StepWaveTM ion optics Video overview of the StepWaveTM technology: Video overview of the TriwaveTM technology: Waters Synapt G2-S Brochure. The SYNAPT G2-S Mass Spectrometer. Calibrating To calibrate LC systems, follow acceptable calibration methods using at least five standards to generate a standard curve. Providing the highest performance, without compromise, the ionization source options are quick and easy to interchange. With Waters leading MS Informatics, SYNAPT G2-S will. SYNAPT G2-S combines revolutionary high performance StepWave™ ion optics, Quantitative Tof.
In the example shown in the attached ppt file, there are three major peaks for Oleic acid (m/z = 281. Customer uses tune file created for troubleshooting a low-sensitivity problem on high m/z ions. Schematic of Synapt G2 and G1. View online or download Waters Xevo G2-XS QTof Overview And Maintenance Manual.
In addition, the HDMS version of the system provides ion mobility mode. Synapt G2-S HDMS (Waters). SYNAPT G2-S HDMS is a mass spectrometer that uses the extra dimension of ion mobility separations to maximize selectivity and confidence in results. Contents Topic Page Waters MALDI SYNAPT G2 HDMS 1-2.
Synapt G2 and G1 both have similar instrument schematic except few differences in the IMS cell. Waters contact information Contacting medium Information Internet The Waters Web site includes contact information for Waters locations worldwide. The ACQUITY UPLC system includes a binary solvent manager, sample manager, column heater, sample organizer, detectors, and a specialized ACQUITY UPLC column. Designed for leading researchers working at the limits of conventional mass spectrometery capabilities who need to further characterize and define their samples, Waters Synapt TM HDMS TM system offers unique, enabling functionality.
With high-efficiency T-Wave ion mobility, you can use manual of waters synapt g2 ppt an additional dimension of separation, based on molecular size and shape. Hi colleagues,We realy do want some feedback from users of Synapt G2 HDMS system. Transforming Your Capacity for Discovery, Understanding, and Success.
Synapt G1 High Definition Mass Spectrometer. Refurbished & Certified Waters Mass Spectrometers. Sometimes chromatography and mass resolution are not enough. Under positive polarity, select the reference compound from the drop-down menu for the mode in which the data were acquired (“Resolution” in the example below). The instrument is equipped with conventional and nano- electrospray ionization sources. Check that V eff is set correctly; Ensure that resolution and peak shape is suitably tuned for the mode used (sensitivity, resolution, or high resolution) using pusher offset and reflectron grid parameters. However, there is no guarantee yet. Open the tune page in MassLynx.
maintain the source component of a MALDI SYNAPT G2-Si system. These are the primary instruments we use for our research purpose. We know the theoretical aspects and specifications of the system. Waters designed the SYNAPT® G2-S Mass Spectrometer to be used as a research tool to deliver authenticated, exact-mass measurement. © Waters Corporation 19 Manual Annotation= Days to Weeks. Synapt G2 is a q-TOF hybrid instrument, mainly used for small molecule mass analysis and hydrogen/deuterium exchange-mass spectrometry (HDX-MS). G1 lacks the helium cell.
synapt g2-si hdms The SYNAPT G2-Si High Definition Mass Spectrometer from Waters is a hybrid-quadrupole, ion-mobility, orthogonal-acceleration time-of-flight (oa-ToF) mass spectrometer that combines high resolution mass spectrometry with high-efficiency ion mobility-based measurements and separation (IMS). I&39;m using Waters Acquity UPLC-Synapt G2 Mass spec for the analysis of the whole metabolite from a group of cell lines. In this tune file, the quad profile is set to a manual profile in both positive and negative resolution mode. The second generation SYNAPT™ G2 platform from Waters provides a new dimension of performance to drive scientific discovery like never before. 1 PC workstation. SYNAPT G2 —QuanTof —MSE —HDMS – Ion Mobility © Waters Corporation 3. evolution of Waters SYNAPT technology. Quadrupole ZSpray™ Source SYNAPT G2-S combines revolutionary StepWave™ ion optics with proven Quantitative Tof (QuanTof™) and High Definition MS™ technologies to provide the highest levels of sensitivity, selectivity, and speed.
Synapt G2Si mass spectrometer, with a mass range up to 100,000 on m/z scale in resolution mode, provides unique separation capability of highly complex samples (in addition to HPLC) by waters its advanced T-wave ion-mobility technology. Waters source technology for second-generation SYNAPT G2 platform enables the widest range of ionization techniques to be utilized universally across a single analytical platform. Fill out the details for the calibration profile as shown below, setting the mass range as before and selecting manual calibration. We have 1 Waters SYNAPT G2 manual available for free PDF download: Operator&39;s, Overview And Maintenance Manual Waters SYNAPT G2 Operator&39;s, Overview And Maintenance Manual (236 pages). Waters SYNAPT HDMS System enables the analysis of samples differentiated by size and shape, as well as mass, to deliver increased specificity and sample definition beyond that achievable by conventional mass spectrometers. FIX or WORKAROUND.
Our lab is equipped with ion mobility-mass spectrometry instrument in the form of Synapt G1 and G2 instrument (Waters). mzML: it depends on the export method by the ProteoWizard program etc. Wait for the epc to boot (the flashing white/purple light on the Synapt G2/S/Si will stop flashing and will remain solid white/purple).
Waters contact information Contacting medium Information Internet The Waters Web site includes contact information for Waters locations worldwide.
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